(<i>R</i>)-(+)-8-Hydroxy-DPAT hydrobromide

产品名称：

78095-19-9
(R)-(+)-8-Hydroxy-DPAT hydrobromide
(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide
(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide

产品介绍：

产品说明

应用

(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:

in mice to test the activity of the serotonin receptor
to test its effect on zebrafish melanocyte migration and survival
to stimulate hippocampal neurons

包装

5, 25, 100 mg in glass bottle

生化/生理作用

(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.
(R)-(+)-8-Hydroxy-DPAT is a full 5-HT_1A serotonin receptor agonist; active enantiomer of (±)-8-hydroxy-DPAT.

基本信息

经验(实验)分子式	C₁₆H₂₅NO · HBr
分子量	328.29
MDL编号	MFCD00153810
PubChem化学物质编号	24278480
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
旋光性	[α]25/D +68.2°, c = 1 in methanol(lit.)
储存条件	protect from light
颜色	white to off-white
溶解性	H₂O: >10 mg/mL at ±60 ℃ (with sonication)
SMILES string	Br.CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1
InChI	1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1
InChI key	BATPBOZTBNNDLN-PFEQFJNWSA-N
Gene Information	human ... HTR1A(3350)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)