(<I>S</I>)-5-氨基磺酰基-N-[(1-乙基-2-吡咯烷基)甲基]-2-甲氧基苯甲酰胺

产品名称：

23672-07-3
(S)-(-)-Sulpiride
Levosulpiride
(S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
(S)-(-)-止呕灵
(S)-5-氨基磺酰基-N-[(1-乙基-2-吡咯烷基)甲基]-2-甲氧基苯甲酰胺
左舒必利

产品介绍：

产品说明

应用

(S)-(−)-Sulpiride was used to study the effect of dopamine D₂ receptor function on activation of KCNQ potassium channels¹⁰ and on depression-like behavior in ovariectomized female rats.¹¹

包装

5, 10 g in poly bottle

生化/生理作用

(S)-(−)-Sulpiride or Levosulpiride blocks the inhibitory enteric D₂ receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.^7,8 Since dopamine controls human sexual function, (S)-(−)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.⁹
D₂ 多巴胺受体拮抗剂；安定药。

特点和优势

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₁₅H₂₃N₃O₄S
分子量	341.43
MDL编号	MFCD00055220
PubChem化学物质编号	24278709
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (titration)
mp	183-186 ℃ (lit.)
创始人	Sanofi Aventis
储存温度	2-8℃
SMILES string	CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
InChI	1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
InChI key	BGRJTUBHPOOWDU-NSHDSACASA-N
Gene Information	human ... DRD2(1813), DRD3(1814) rat ... Adra1a(29412), Drd2(24318), Drd3(29238), Htr1a(24473), Htr2a(29595)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable