产品说明
应用
Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.
包装
5 mg in glass bottle
25, 100 mg in poly bottle
生化/生理作用
Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.
注意
光敏性
基本信息
经验(实验)分子式 | C19H20ClNO2 · HBr |
分子量 | 410.73 |
MDL编号 | MFCD00069235 |
PubChem化学物质编号 | 24277890 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
形式 | solid |
颜色 | tan |
溶解性 | H2O: 3.7 mg/mL aqueous base: unstable ethanol: soluble |
储存温度 | 2-8℃ |
SMILES string | Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3 |
InChI | 1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H |
InChI key | WLXGFAVTAAQOFH-UHFFFAOYSA-N |
Gene Information | human ... DRD1(1812) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich