产品说明
包装
5 g in poly bottle
生化/生理作用
Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic
特点和优势
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式 | C20H24ClN3S · 2C4H4O4 |
分子量 | 606.09 |
EC 号 | 201-511-3 |
MDL编号 | MFCD00069330 |
PubChem化学物质编号 | 57654570 |
NACRES | NA.77 |
产品性质
质量水平 | 200 |
溶解性 | H2O: slightly soluble 0.3 mg/mL 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL methanol: soluble |
创始人 | GlaxoSmithKline |
SMILES string | OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 |
InChI | 1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1- |
InChI key | DSKIOWHQLUWFLG-SPIKMXEPSA-N |
Gene Information | human ... DRD2(1813) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H336 - H361d - H362 |
预防措施声明 | P202 - P260 - P263 - P264 - P301 + P312 - P308 + P313 |
危险分类 | Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3 |
靶器官 | Central nervous system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich