产品说明
一般描述
Tolfenamic acid is a fenamate and is made up of a monocarboxylate diphenylamine nucleus.
应用
Tolfenamic acid has been used in Arabidopsis bud assay for activity comparison with quinazolinedione derivatives (QADD) based compounds.
包装
5 g in glass bottle
生化/生理作用
Tolfenamic acid is involved in the inhibition of prostaglandin synthesis. It also plays a role in apoptosis of head and neck cancer cells.
Non-steroidal anti-inflammatory agent. Interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor.
基本信息
经验(实验)分子式 | C14H12ClNO2 |
分子量 | 261.70 |
EC 号 | 237-264-3 |
MDL编号 | MFCD00133865 |
PubChem化学物质编号 | 24899896 |
NACRES | NA.77 |
产品性质
质量水平 | 200 |
测定 | ≥98% (TLC) |
形式 | powder |
溶解性 | ethanol: 50 mg/mL, clear, greenish-yellow |
SMILES string | Cc1c(Cl)cccc1Nc2ccccc2C(O)=O |
InChI | 1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18) |
InChI key | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P301 + P310 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
Sigma-Aldrich