9-（2-脱氧-β-<SC>D</SC>-呋喃核糖基）鸟嘌呤

产品名称：

312693-72-4
2′-Deoxyguanosine monohydrate
9-(2-Deoxy-β-D-ribofuranosyl)guanine
Guanine-2′-deoxyriboside
2'-脱氧鸟苷一水合物
9-（2-脱氧-β-D-呋喃核糖基）鸟嘌呤
鸟嘌呤-2′-脱氧核苷

产品介绍：

产品说明

应用

2′-Deoxyguanosine monohydrate has been used as a nucleoside supplement:

to study its effect on mitochondrial DNA copy number in deoxyguanosine kinase (dguok) mutant zebrafish,
in tissue culture medium for deoxyribonucleotide triphosphate (dNTP) synthesis,
in RPMI (Roswell Park Memorial Institute)-1640 medium to eliminate the endogenous thymocytes

包装

1, 5 g in poly bottle
25, 100 mg in poly bottle

生化/生理作用

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphorylation (kinases) forms deoxyguanosine triphosphate (dGTP) which is used by DNA polymerases and reverse transcriptases to synthesize DNA(s). Deoxyguanosine is the most electron-rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

基本信息

经验(实验)分子式	C₁₀H₁₃N₅O₄ · H₂O
分子量	285.26
Beilstein	39814
MDL编号	MFCD00150760
PubChem化学物质编号	24894083
NACRES	NA.51

产品性质

质量水平	200
生物来源	synthetic (organic)
测定	99-100%
形式	powder
溶解性	1 M NH₄OH: 50 mg/mL, clear, colorless
SMILES string	O.NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](CO)O3)C(=O)N1
InChI	1S/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1
InChI key	LZSCQUCOIRGCEJ-FPKZOZHISA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

2′-Deoxyguanosine monohydrate

2'-脱氧鸟苷 一水合物

2'-脱氧鸟苷一水合物