产品说明
一般描述
Drebrin (Developmentally-regulated brain protein) is also known by the gene name DBN1. Drebrins are found in the cytoplasm of brain neurons as well as tissues including heart, placenta skeletal muscle kidney and pancreas. Debrin binds F-actin and is involved in the mechanisms of development, cell migration, neuronal processes and dendrite plasticity.
免疫原
KLH-conjugated linear peptide corresponding to human DBN1.
应用
Immunohistochemistry Analysis: A 1:4,000 dilution from a representative lot detected DBN1 in human cerebellum and rat midbrain tissues.
This DBN1 antibody is validated for use in WB & IHC for the detection of the DBN1 protein.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
质量
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected DBN1 in 10 µg of mouse brain tissue lysate.
目标描述
~110 kDa observed. The calculated molecular weight is 71 kDa, however DBN1 has been shown as a ~110 kDa band in western blotting (Maezawa, I., et al. (2006). Novus Biologicals. 1-2).
联系
Replaces: AB15288
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Mouse brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | horse, human, rat, mouse |
species reactivity (predicted by homology) | bovine (based on 100% sequence homology), equine (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
NCBI登记号 | NP_004386 |
UniProt登记号 | Q16643 |
运输 | wet ice |
Gene Information | human ... DBN1(1627) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich