产品说明
一般描述
ST6GAL1, also known as Beta-galactoside alpha-2/ 6-sialyltransferase 1, or Alpha 2/ 6-ST 1, and encoded by the gene symbol ST6GAL1/ SIAT1, is a member of the glycosyltransferase 29 family. ST6GAL1 has been implied to play an important role in the transfer of sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. The membrane-bound form of ST6GAL1 is located in trans-cisternae of Golgi apparatus. The soluble form of ST6GAL1 is derived from the membrane form by proteolytic processing. ST6GAL1 is located in the Golgi apparatus, Golgi stack membrane, and the Single-pass type II membrane protein.
免疫原
Epitope: Lumenal domain
KLH-conjugated linear peptide corresponding to the Lumenal domain of human ST6GAL1.
应用
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ST6GAL1 in human prostate and human liver cancer tissue.
Research Sub Category
Apoptosis - Additional
Anti-ST6GAL1 is an antibody against ST6GAL1 for use in WB, IH.
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blotting in human skeletal muscle tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected ST6GAL1 in 10 µg of human skeletal muscle tissue lysate.
目标描述
~41 kDa observed. The calculated molecular weight is 47 kDa, however ST6GAL1 has been shown as a ~41 kDa band in western blots (Minyoung, L., et al. (2008). Mol. Cancer Research. 6:1316-1325).
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI登记号 | NP_003023 |
UniProt登记号 | P15907 |
运输 | wet ice |
Gene Information | human ... ST6GAL1(6480) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich