产品说明
一般描述
Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is expressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate.
免疫原
KLH-conjugated linear peptide corresponding to the C-terminus of Human Wnt-11.
应用
This Anti-Wnt-11 Antibody is validated for use in Western Blotting for the detection of Wnt-11.
质量
Evaluated by Western Blot in human osteosarcoma U2OS cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected WNT-11 in 10 µg of human osteosarcoma U2OS cell lysate.
目标描述
~39 kDa observed
外形
Antigen Affinity Purified
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
species reactivity (predicted by homology) | bovine (based on 100% sequence homology), rat (based on 100% sequence homology), rabbit (based on 100% sequence homology), mouse (based on 100% sequence homology) |
technique(s) | western blot: suitable |
NCBI登记号 | NP_004617 |
UniProt登记号 | O96014 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich