产品说明
一般描述
Vacuolar protein sorting-associated protein 4 (Vps4) is a member of the AAA protein family (ATPases associated with diverse cellular activities). Vps4 exists as two orthologs in humans (VPS4A and VPS4B). The gene encoding Vps4A is mapped to chromosome 16q22, while the gene for Vps4B resides on chromosome 18q21-q22.
特异性
Anti-VPS4 recognizes human, mouse, and rat VPS4A and VPS4B.
应用
Anti-VPS4 antibody has been used in
生化/生理作用
Vacuolar protein sorting-associated protein 4 (VPS4) mediates endosomal membrane protein sorting, retroviral budding and cytokinesis by recognizing membrane-associated ESCRT-III assemblies and catalyzing their disassembly.
外形
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
储存及稳定性
Store at –20 ℃. For continuous use, the product may be stored at 2–8 ℃ for up to one month. For extended storage, freeze in working aliquots at –20 ℃. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~50 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunoprecipitation (IP): 2-4 μg using lysates of human HeLa cells western blot: 1-2 μg/mL using whole extracts of mouse 3T3 or rat NRK cells |
| UniProt登记号 | Q9UN37 |
| application(s) | research pathology |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... VPS4A(27183) mouse ... Vps4a(116733) rat ... Vps4a(246772) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
