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Anti-RIPK1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500420
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
5531.3 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-RIPK1 antibody produced in rabbit
Anti-RIP
Anti-RIP1
Anti-Receptor-interacting serine/threonine-protein kinase 1
产品介绍:

产品说明

一般描述

Receptor interacting serine/threonine kinase 1 (RIPK1) gene is located at 6p25.2 on the human chromosome. It belongs to the RIPK family. RIPK1 is a necroptosis regulatory protein. It is made up of N-terminal kinase domain, a RIP homotypic interaction motif and its C-terminal contains the death domain.

免疫原

RIPK1 antibody was raised against a 15 amino acid peptide from near the amino terminus of human RIPK1.

应用

Anti-RIPK1 antibody produced in rabbit has been used in:

  • western blotting
  • immunocytochemistry
  • immunofluorescence

生化/生理作用

Receptor interacting serine/threonine kinase 1 (RIPK1) is involved in inflammatory signaling and prosurvival. It is also involved in regulating the caspase-8-mediated apoptosis. RIPK1 plays a role in activating nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein (MAP) kinases. Mutations in this gene is associated with impaired innate and adaptive immunity. It also leads to very early onset inflammatory bowel diseases (VEO-IBDs).
Receptor interacting serine/threonine kinase 1 (RIPK1) modulates cell survival and death. It also has a role in inflammation.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500420.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01633826
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman, rat, mouse
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登记号NP_003795
UniProt登记号Q13546
运输dry ice
储存温度−20℃
Gene Informationhuman ... RIPK1(8737)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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