产品说明
一般描述
G-protein coupled receptor bonzo (BONZO), also known as C-X-C chemokine receptor type 6 (CXCR6,CXC-R6,CXCR-6), CDw186 (CD186), G-protein coupled receptor STRL33 (STRL33), and TYMSTR, is a receptor for the C-X-C chemokine CXCL16 and is shown to be used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Certain G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b have been identified as HIV coreceptors. BONZO is expressed in lymphoid tissues and activated T cells.
特异性
This antibody recognizes the N-terminus of Bonzo.
免疫原
KLH-conjugated linear peptide corresponding to the N-terminus of human Bonzo.
应用
Detect CXCR6 using this rabbit polyclonal antibody, Anti-Bonzo Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 20 µg/mL from a representative lot detected Bonzo in human spleen tissue.
质量
Evaluated by Western Blotting/Peptide Inhibition Assay in human spleen tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected Bonzo in 15 µg of human spleen tissue lysate.
目标描述
~45 kDa observed. Uncharacterized bands may appear in some lysate(s).
外形
Antigen Affinity Purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | O00574 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich