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位置:首页 > 品牌 > Sigma-Aldrich > Anti-CUX1 Antibody, a.a. 861

Anti-CUX1 Antibody, a.a. 861

品牌
Sigma-Aldrich
货号
ABE217
规格纯度
from rabbit, purified by affinity chromatography
参考价格
5909.34 *本价格含增值税费
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数量
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产品名称:
Anti-CUX1 Antibody, a.a. 861
Homeobox protein cut-like 1, CCAAT displacement protein, CDP, Homeobox protein cux-1
产品介绍:

产品说明

一般描述

Homeobox protein cut-like 1 (CUX1) is also known as CCAAT displacement protein (CDP) and Homeobox protein cux-1. CUX1 is thought to repress expression of developmentally regulated genes involved in mammalian development, likely through the prevention of CCAAT factor binding at promoters. CUX1 also represses T-cell receptor (TCR) beta enhancer function by binding to matrix attachment region beta (MARbeta), and is a component of the nf-munr repressor, which binds to matrix attachment regions (MARs) of the immunoglobulin heavy chain enhancer.

特异性

This antibody recognizes the region of amino acids beginning at 861 of CUX1. This antibody is expected to cross react with all known isoforms of CUX1.
Other homologies: Mouse (95% sequence homology).

免疫原

Epitope: Region of amino acids beginning at 861
GST-tagged recombinant protein corresponding to a region of amino acids beginning at 861 of human CUX1.

应用

Research Sub Category
Transcription Factors
Immunoprecipitation Analysis: 1.25 µg from a representative lot immunoprecipitated CUX1 in 500 µg of HeLa nuclear extract.

Alexa Fluor® is a registered trademark of Life Technologies.
Detect Cux1 using this rabbit polyclonal antibody, Anti-CUX1 Antibody, a.a. 861 validated for use in western blotting & IP.
Research Category
Epigenetics & Nuclear Function

质量

Evaluated by Western Blotting in HeLa nuclear extract.

Western Blotting Analysis: 0.25 µg/mL from a representative lot detected CUX1 in 10 µg of HeLa nuclear extract.

目标描述

~200 kDa and ~110 kDa observed. Uniprot describes 11 different isoforms. A full length protein has been described at 200 kDa and is proteolytically cleaved into the p150, p110, p90, and p80 isoforms. Additionally, the p75 isoform is the result of alternative splicing (Sansregret, L, et al. (2008). Gene. 412(1-2):84-94.). Uncharacterized band(s) may be observed in some cell lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HeLa nuclear extract

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityhuman
technique(s)immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号NP_853530
UniProt登记号P39880
运输wet ice
Gene Informationhuman ... CUX1(1523)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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