产品说明
一般描述
Anti-Cytochrome c antibody detects endogenous levels of total Cytochrome c protein.
The cytochrome c gene is mapped to human chromosome 7p15.3. The encoded protein consists of two thioether present between heme and two cysteine residues included in a CXXCH motif (highly conserved). It is localized to mitochondrial intermembrane space.
免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome c.
Immunogen Range: 10-59
应用
Anti-Cytochrome c, N-terminal antibody produced in rabbit has been used in western blot analysis.
生化/生理作用
Cytochrome c is a water-soluble intermediary of electron transport chain. It acts as an ROS (reactive oxygen species) scavenger, and involved in redox-mediated protein import and apoptosis. Cytochrome c has peroxidase activity, contributing towards intrinsic pathway of apoptosis.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 11 kDa |
species reactivity | mouse, human, rat |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:10000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI登记号 | P99999 |
UniProt登记号 | P99999 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... CYCS(54205) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich