您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Anti-LMX-1 Antibody

Anti-LMX-1 Antibody

品牌
Sigma-Aldrich
货号
AB10533
规格纯度
serum, from rabbit
参考价格
6526.19 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-LMX-1 Antibody
LIM homeobox transcription factor 1, alpha, LIM/homeobox protein 1.1, LIM/homeobox protein LMX1A
产品介绍:

产品说明

一般描述

LMX-1 is a transcription factor that belongs to the LIM-homeodomain (LIM-HD) transcription factor family. It is induced within the ventral midbrain as a response to early signaling. LMX-1 is a necessary component for the development of the roof plate and for CNS dorsal cell date specification and the development of vertebrae. It is Expressed in roof plate, an organizational locus found in the dorsal CNS that functions to moderate the differentiation and specification of adjacent neurons through the secretion of signaling molecules such as WNT and BMP. Recent studies have indicated that LMX-1 has high potential for stimulating the production of mesencephalic dopamine neurons(mesDA) for the therapeutic treatment Parkinson disease, a condition characterized by dopaminergic neurotransmission decline resulting from the progression of mesDA neuronal degeneration within the substantia nigra pars compacta (SN).

特异性

This antibody recognizes LMX-1.

免疫原

Epitope: C-terminus
GST-tagged recombinant protein corresponding to the C-terminus of hamster LMX-1.

应用

Research Sub Category
Neuronal & Glial Markers
Anti-LMX-1 Antibody is an antibody against LMX-1 for use in WB.
Research Category
Epigenetics & Nuclear Function

质量

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected LMX-1 on 10 µg of mouse testis tissue lysate.

目标描述

~50 kDa observed.

外形

Unpurified rabbit polyclonal serum containing 0.05% sodium azide.
Unpurified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
Mouse testis tissue lysate

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式serum
antibody product typeprimary antibodies
克隆polyclonal
species reactivitymouse, rat
species reactivity (predicted by homology)hamster (based on 100% sequence homology)
technique(s)western blot: suitable
同位素/亚型IgG
GenBank® accession no.AAB62320
UniProt登记号Q04650
运输wet ice

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1

Sigma-Aldrich

推荐产品