Anti-NOX4 Antibody

产品名称：

Anti-NOX4 Antibody
NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase

产品介绍：

产品说明

一般描述

NOX4 (NADPH oxidase 4) is a phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes with resultant antimicrobial activity and has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erythropoietin in the renal cortex.

免疫原

Linear peptide corresponding to the C-terminus of human NOX4.

应用

Research Sub Category
Apoptosis - Additional
Immunohistochemistry Analysis: A 1:500 and a 1:50 dilution from a representative lot detected NOX4 in human kidney and skeletal muscle tissues, respectively.

Immunohistochemistry Analysis:: A representative lot detected NOX4 in mouse liver tissue (I. Fabregat, IDIBELL, Barcelona, Spain).

Immunocytochemistry Analysis: A representative lot detected NOX4 in Hep3B cells (Esther Bertran, IDIBELL, Barcelona, Spain).

Immunohistochemistry Analysis: A representative lot detected NOX4 in mouse liver tissues expressing wildtype Mdr2/p19, or knockout Mdr2 ARF or knockout Stat3/Mdr2 (Sancho, P. et al. (2012). PLoS One. 7(9):e45285.).
Research Category
Apoptosis & Cancer
Anti-NOX4 Antibody is a highly specific rabbit polyclonal antibody, that targets NADPH Oxidase (phox) & has been tested in IHC & ICC.

质量

Evaluated by Immunohistochemistry in human kidney tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected NOX4 in human kidney tissue.

目标描述

67 kDa calculated

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein A purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

产品性质

生物来源	rabbit
质量水平	100
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	polyclonal
species reactivity	mouse, human
species reactivity (predicted by homology)	rat (based on 100% sequence homology)
technique(s)	immunocytochemistry: suitable immunohistochemistry: suitable
NCBI登记号	NP_001137308
UniProt登记号	Q9NPH5
运输	wet ice
Gene Information	human ... NOX4(50507)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable