产品说明
一般描述
PKC α (protein kinase C α) gene is mapped to 17q24.2. PKC α is expressed in heart, liver, brain and epithelium.
Anti-PKC α Antibody detects endogenous levels of total PKC α protein.
免疫原
The antiserum was produced against synthesized peptide derived from human PKC alpha.
Immunogen Range: 606-655
生化/生理作用
PKC (protein kinase C) is known to mediate different cellular processes, such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. While PKC is also associated with the learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC α (protein kinase C α) being one of the isozymes of the PKC family, it catalyzes the phosphorylation of substrates with many peptides.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 76 kDa |
species reactivity | mouse, rat, human |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:1000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI登记号 | P17252 |
UniProt登记号 | P17252 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... PRKCA(5578) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich