产品说明
一般描述
p53 upregulated modulator of apoptosis (PUMA) protein is a member of the B-cell lymphoma 2 (BCL2) family. It is a pro-apoptotic BCL-2 homology 3 (BH3)-only protein and has a small BH3 domain. The PUMA gene is mapped on the human chromosome at 19q13.32.
免疫原
synthetic peptide corresponding to amino acids 2 to 16 of human PUMA-α.
应用
Anti-PUMA/bbc3, N-Terminal antibody produced in rabbit has been used in western blotting and immunoprecipitation.
生化/生理作用
p53 upregulated modulator of apoptosis (PUMA) acts as a determinant of the levels of germ cells during ovarian development. It promotes apoptosis in various cellular stress insults. Deletion of the PUMA gene is observed in several kinds of human cancers.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD04040565 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~23 kDa |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | microarray: suitable western blot: 2-4 μg/mL |
| UniProt登记号 | Q96PG8 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... BBC3(27113) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
