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Anti-Bax antibody produced in rabbit

抗 BAX 兔抗

品牌
Sigma-Aldrich
货号
SAB4502546
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Bax antibody produced in rabbit
BCL2L4
Apoptosis regulator BAX
BAX
Bcl-2-like protein 4
Bcl2-L-4
抗 BAX 兔抗
产品介绍:

产品说明

一般描述

The BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) gene is mapped to human chromosome 19q13.33. It codes for α-helical globular protein. The protein contains eight amphipathic helices around a hydrophobic helix. Bax is known to be mostly localized in the cytoplasm.
Anti-BAX antibody detects endogenous levels of total BAX protein.

免疫原

The antiserum was produced against synthesized peptide derived from human Bax.

Immunogen Range: 133-182

应用

Anti-BAX, C-Terminal antibody produced in rabbit has been used in western blotting analysis.

生化/生理作用

BAX (BCL2 (B-cell lymphoma 2) associated X, apoptosis regulator) is predominantly associated with cellular homeostasis, cell cycle and pathogenesis of cell death particularly in cancer cells. In response to an apoptotic stimulus, Bax brings about mitochondrial dysfunction and apoptosis. Oligomerization of bax promotes mitochondrial outer membrane permeabilization.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 21 kDa
species reactivityhuman, rat, mouse
浓度~1 mg/mL
technique(s)ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号Q07812
UniProt登记号Q07812
运输wet ice
储存温度−20℃
Gene Informationhuman ... BAX(581)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg

Sigma-Aldrich

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