产品说明
一般描述
The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport.
特异性
NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
免疫原
KLH-conjugated linear peptide corresponding to human NIPSNAP2.
应用
Detect the NIPSNAP2 protein using this Anti-NIPSNAP2 validated for use in WB & IHC.
Immunohistochemistry Analysis: 2.5µg/mL of this antibody from a representative lot detected NIPSNAP2 in mouse skeletal muscle tissue.
质量
Evaluated by Western Blot in human skeletal muscle tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected NIPSNAP2 in 15 µg of human skeletal muscle tissue lysate.
目标描述
~31 kDa observed
外形
Antigen Affinity Purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, mouse |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | O75323 |
运输 | wet ice |
Gene Information | human ... GBAS(2631) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich