Anti-phospho-Fyn (pTyr⁵³⁰) antibody produced in rabbit

产品说明

一般描述

Tyrosine-protein kinase FYN is a neuronally enriched cytoplasmic protein. It is encoded by the genes mapped to human chromosome 6q21. FYN protein belongs to the proto-oncogene tyrosine-protein kinase, Src family.

免疫原

The antiserum was produced against synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530.

Immunogen Range: 488-537

应用

Anti-phospho-Fyn (pTyr530) antibody produced in rabbit has been used in immunoprecipitation and immunoblotting.

生化/生理作用

Tyrosine-protein kinase FYN and phospho-FYN act as signaling systems for spatial memory. Phospho-FYN plays a vital role in the regulation of oligodendrocyte myelination and neurofilament phosphorylation. FYN aids in the development and activation of T cells in various physiological conditions. Overexpression of the FYN gene has been observed in various types of cancer.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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