产品说明
一般描述
SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).
特异性
At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.
免疫原
KLH-conjugated linear peptide corresponding to human SAPAP2.
应用
Research Sub Category
Synapse & Synaptic Biology
Immunohistochemistry Analysis: 5 µg/mL of this antibody from a representative lot detected SAPAP2 in human brain tissue.
Research Category
Neuroscience
This SAPAP2 antibody is validated for use in WB & IHC for the detection of the SAPAP2 protein.
质量
Evaluated by Western Blot in L1210 cell lysate.
Western Bloting Analysis: 1 µg/mL of this antibody detected SAPAP2 in 15 µg of L1210 cell lysate.
目标描述
~114 kDa observed. Uncharacterized bands may be observed.
外形
Purified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
L1210 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse, human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | Q9P1A6 |
运输 | wet ice |
Gene Information | human ... DLGAP2(9228) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich