产品说明
一般描述
Tripartite motif-containing protein 5 (TRIM5), also known as the RING finger protein 88 (RNF88), is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. The TRIM5 delta isoform has been shown to colocalize with BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells serving as a scaffold for the assembly of endogenous BTBD proteins.
免疫原
KLH-conjugated linear peptide corresponding to human TRIM5 delta.
应用
Anti-TRIM5 delta Antibody is a highly specific rabbit polyclonal antibody, that targets Tripartite motif-containing protein 5 & has been tested in western blotting & IHC.
Research Sub Category
Immunoglobulins & Immunology
Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected TRIM5 delta in mouse brain tissue.
Research Category
Inflammation & Immunology
质量
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 delta in 15 µg of mouse brain tissue lysate.
目标描述
~25 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa
外形
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Mouse brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse |
species reactivity (predicted by homology) | human (immunogen homology) |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | Q9C035 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich