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Rabbit anti-Vimentin Antibody, Affinity Purified

品牌
Sigma-Aldrich
货号
PLA0199
规格纯度
Powered by Bethyl Laboratories, Inc.
参考价格
5699.93 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Rabbit anti-Vimentin Antibody, Affinity Purified
CTRCT30
HEL113
epididymis luminal protein 113
产品介绍:

产品说明

一般描述

Vimentin is a specific type III intermediate filament (IF) protein. It is abundantly expressed in mesenchymal cells. The gene encoding this protein is localized on human chromosome 10p13.

免疫原

The epitope recognized by PLA0199 maps to a region between residue 416 and 466 of human vimentin using the numbering given in entry NP_003371.2 (GeneID 7431).

生化/生理作用

Vimentin helps to preserve the structure of cell and stability of tissue in mesenchymal cells. It is involved in tumorigenesis, EMT (epithelial mesenchymal transition) and the metastatic spread of cancer. It also controls infectious internalization of human papillomavirus 16 pseudovirions.

外形

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他说明

Vimentin is an intermediate filament expressed mainly in mesenchymal tissue and in primitive (undifferentiated) non-mesenchymal cells. It is a Class III cytoplasmic filament that forms a dense cytoskeletal network that extends from the nucleus to the plasma membrane. Vimentin reorganization during mitosis is likely regulated via its multiple phosphorylation sites. Vimentin expression is also found in mesoderm derived epithelia. Immunohistochemistry (IHC) with anti-vimentin antibodies is often used to identify neoplasms of mesenchymal or mesodermal origin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity purified immunoglobulin
antibody product typeprimary antibodies
等级Powered by Bethyl Laboratories, Inc.
species reactivitymouse, human
technique(s)immunohistochemistry: 1:200-1:1,000
western blot: 1:2,000- 1:10,000
登记号NP_003371.2
运输wet ice
储存温度2-8℃
Gene Informationrabbit ... Vimentin(7431)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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