产品说明
一般描述
The antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
免疫原
Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Yp-I-V), according to the protein NP_004084.1
特点和优势
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目标描述
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5′ UTR but that encode the same protein have been identified for this gene.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~37 kDa |
| species reactivity | rat, human, mouse |
| 浓度 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (P-V-Yp-I-V) |
| NCBI登记号 | NM_004093.2 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SEPTIN1(1948) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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