Anti-Pontin antibody, Mouse monoclonal

产品名称：

Anti-Pontin antibody, Mouse monoclonal
Anti-49 kDa TBP-interacting protein
Anti-TAP54-alpha
Anti-nuclear matrix protein 238
Anti-RUVBL1
Anti-NMP 238
Anti-ECP-54
Anti-49 kDa TATA box-binding protein-interacting protein
Anti-RuvB (e coli homolog)-like 1
Anti-INO80 complex subunit H
Anti-RuvB-like 1
Anti-Pontin52
Anti-TIH1
Anti-TIP60-associated protein 54-alpha
Anti-54 kDa erythrocyte cytosolic protein
Anti-TIP49
Anti-RVB1
Anti-TIP49A

产品介绍：

产品说明

一般描述

Monoclonal Anti-Pontin (mouse IgG1 isotype) is derived from the hybridoma 5G3-11 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human pontin fusion protein. Pontin and reptin are two related members of the AAA+ (ATPases associated with diverse cellular activities) family of ATPases. Pontin and reptin share some homology to the bacterial RuvB gene.

免疫原

human Pontin fusion protein

应用

Monoclonal Anti-Pontin antibody produced in mouse has been used in:

western blotting
immunoprecipitation
ChIP-sequencing
immunohistochemistry
immunofluorescence
RNA immunoprecipitation

生化/生理作用

Pontin and Reptin are associated with several chromatin-remodeling complexes and are involved in multiple biological processes including chromatin remodeling, DNA damage repair, transcriptional regulation, telomerase activity, apoptosis and cancer metastasis. Both proteins are also involved in cellular transformation by beta-catenin and c-myc through their chromatin remodeling function.

外形

Solution in 0.01 M phosphate buffered saline, 7.4 pH, containing 15 mM sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

产品性质

质量水平	200
生物来源	mouse
偶联物	unconjugated
抗体形式	purified from hybridoma cell culture
antibody product type	primary antibodies
克隆	5G3-11, monoclonal
形式	buffered aqueous solution
分子量	~50 kDa
species reactivity	monkey, human, canine
technique(s)	immunohistochemistry: suitable immunoprecipitation (IP): suitable indirect immunofluorescence: suitable western blot: 1:1,000-1:2,000 using whole extracts of human HEK-293T or MCF-7 cells
同位素/亚型	IgG
UniProt登记号	Q9Y265
运输	dry ice
储存温度	−20℃
Gene Information	human ... RUVBL1(8607)

安全信息

储存分类代码	12 - Non Combustible Liquids
闪点(F)	Not applicable
闪点(C)	Not applicable