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位置:首页 > 品牌 > Sigma-Aldrich > Anti-phospho Histone H3 (Ser10), Alexa Fluor® 647 Conjugate Antibody

Anti-phospho Histone H3 (Ser10), Alexa Fluor® 647 Conjugate Antibody

品牌
Sigma-Aldrich
货号
06-570-AF647
规格纯度
0.5 mg/mL, from rabbit
参考价格
6358.33 *本价格含增值税费
促销
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  • 增值税票
数量
-+
产品名称:
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 647 Conjugate Antibody
H3S10P, Histone H3 (phospho Ser10), H3 histone, family 3A, H3.3A, H3 histone, family 3B, H3.3B
产品介绍:

产品说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 06-570.

免疫原

Linear peptide corresponding to Histone H3 phosphorylated at Ser10.

应用

Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function
Anti-phospho-H3 (Ser10), Alexa Fluor® 647 Conjugate is a purified rabbit polyclonal antibody to detect Histone H3 phosphorylated at serine 10. This Ab is labeled with Alexa Fluor 647 and validated for use in IC. The unconjugated version of this antibody is published and proven in ICC, IP & WB.

质量

Evaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected phospho Histone H3 (Ser10) in HeLa cells.

Alexa Fluor® is a registered trademark of Life Technologies.

目标描述

~17 kDa observed (Refer to Cat. No. 06-570)

外形

Protein A purified
Purified rabbit conjugated antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% Sodium Azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物ALEXA FLUOR® 647
抗体形式purified antibody
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman
species reactivity (predicted by homology)mouse (based on 100% sequence homology)
浓度0.5 mg/mL
technique(s)immunocytochemistry: suitable
NCBI登记号NP_003484.1
UniProt登记号Q16695
运输wet ice
Gene Informationhuman ... HIST1H3F(8968)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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