产品说明
一般描述
GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.
特异性
Recognizes GLUT-8.
免疫原
An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)
Epitope: C-terminus
应用
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling
Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).
质量
Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.
目标描述
Approx. 50 kDa
联系
Replaces: AB3140
外形
ImmunoAffinity Purified
Format: Purified
Liquid in PBS with 0.1% BSA.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
分析说明
Control
Human kidney tissue.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | human |
species reactivity (predicted by homology) | mouse |
technique(s) | immunohistochemistry: suitable (paraffin) |
UniProt登记号 | Q9NY64 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich