产品说明
一般描述
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
特异性
Recognizes HNF3β/FOXA2.
免疫原
GST fusion protein corresponding to residues 7-86 of rat hepatocyte nuclear factor-3 beta / forkhead box A2 (HNF3β/FOXA2)
应用
Research Sub Category
Transcription Factors
Research Category
Epigenetics & Nuclear Function
Detect HNF3β/FOXA2 with Anti-HNF3β/FOXA2 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IHC & WB.
质量
Routinely evaluated by immunoblot with nuclear extracts from MLE 12 cells
目标描述
50 kDa
外形
Format: Purified
Protein A purified
Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative.
储存及稳定性
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
MLE 12 nuclear extracts, human liver lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | human, mouse, rat |
manufacturer/tradename | Upstate® |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG |
UniProt登记号 | Q9Y261 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
Sigma-Aldrich