产品说明
一般描述
PP6R3 (protein Ser/Thr phosphatase 6 regulatory subunit 3), also known as SAPS3 is a regulatory subunit of protein phosphatase 6 which is important for cell survival and is associated with TOR signaling in yeast. PP6R3 has been implicated in the transition from G1 to the S phase of mitosis. The PP6R3 subunit is one of three human versions of SAPs which may also have a role to play in regulation of NF-kappaB.
免疫原
Histidine-tagged-recombinant protein corresponding to human PP6R3.
应用
Anti-PP6R3 Antibody detects level of PP6R3 & has been published & validated for use in WB, IH(P).
Research Category
Signaling
Immunohistochemistry Analysis: 1:200 dilution of a representative lot detected PP6R3 in human kidney and human breast tissues.
Research Sub Category
Kinases & Phosphatases
质量
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 1:10,000 dilution of this antibody detected PP6R3 on 10 µg of HeLa cell lysate.
目标描述
~130-140 kDa observed. UniProt entry describes 6 isoforms produced by alternative splicing ranging from 88.9 to 98.9 kDa
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
HeLa cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
NCBI登记号 | NP_001157634 |
UniProt登记号 | Q5H9R7 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich