Anti-phospho-Histone H3 (Thr3) Antibody

产品说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.



The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

特异性

H3 phosphorylated at Thr3

免疫原

synthetic peptide containing, in which pT corresponds to phosphothreonine at position 3 of human Histone H3

应用

Anti-phospho-Histone H3 (Thr3) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Histone H3 (Thr3) also known as H3T3P, Histone H3 (phospho T3) & has been validated in IF, WB, ICC.
Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function

质量

routinely evaluated by immunoblot in acid extracted proteins from mitotic HeLa cells

目标描述

17 kDa

外形

Format: Unpurified
0.05% sodium azide and 30% glycerol.
Immunodepleted

储存及稳定性

2 years at -20°C

分析说明

Control
Acid extract from colcemid-treated HeLa cells

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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