产品说明

一般描述

PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis.

特异性

Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein.

免疫原

Purified peptide conjugated to KLH.

应用

Research Category
Signaling
Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB.
Research Sub Category
Kinases & Phosphatases

质量

Evaluated by Western Blot in L6 cell lysates.
Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates.

目标描述

Approx. 46 kDa

联系

Replaces: AB4090

外形

Format: Purified
Protein Purified
Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide.

储存及稳定性

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

分析说明

Control
L6 Cell Lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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