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位置:首页 > 品牌 > Sigma-Aldrich > Anti-dimethyl-Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate

Anti-dimethyl-Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate

品牌
Sigma-Aldrich
货号
07-441-AF488
规格纯度
from rabbit, ALEXA FLUOR® 488
参考价格
8371.35 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
Anti-dimethyl-Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate
Histone H3.1t, H3/t, H3t, H3/g, dimethyl-Histone H3 (Lys9), AlexaFluor 488 Conjugate
产品介绍:

产品说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine and the phosphorylation of serine or threonine. Histone H3 variants (H3.1, H3.2 and H3.3) have been implicated in the epigenetic memory of cellular state. Genome-wide patterns of H3 are dependent on amino acid sequence and change with cellular differentiation at developmentally regulated loci.

特异性

Histone H3 dimethylated on lysine 9.

免疫原

Epitope: H3K9me2
KLH-conjugated, 2X-branched synthetic peptide containing the sequence ..RKme2STG.., in which Kme2 corresponds to dimethyl-lysine at residue 9 of human Histone H3.

应用

Research Sub Category
Nuclear Receptors
Anti-dimethyl-Histone H3 (Lys9) Antibody, AlexaFluor 488 Conjugate is an antibody against dimethyl-Histone H3 (Lys9) Antibody for use in Immunocytochemistry.
Research Category
Epigenetics & Nuclear Function
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected dimethyl-Histone H3 (Lys9) in HepG2 cells.
The unconjugated antibody (Cat. No. 07-441) is shown to be suitable also for Western blotting, dot blot, immunocytochemistry, and peptide inhibition assay (peptide blocking) applications.

质量

Evaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected dimethyl-Histone H3 (Lys9) in HeLa cells.

目标描述

~17 kDa observed

外形

Purified rabbit antibody conjugate in PBS with 15 mg/ml BSA and 0.1 % sodium azide.
Protein A purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物ALEXA FLUOR® 488
抗体形式purified antibody
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman, mouse
species reactivity (predicted by homology)yeast (based on 100% sequence homology), rat (based on 100% sequence homology), chicken (based on 100% sequence homology)
technique(s)immunocytochemistry: suitable
NCBI登记号NM_003493
UniProt登记号Q16695
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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