产品说明

一般描述

Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2].

Also available Fmoc-Lys(Dde)-OH 852057.

This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine [3].

The product number for this product was previously 04-12-5201.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

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Replaces: 04-12-5201

分析说明

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(157B)): ≥ 97 %
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 96.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.00 %
For TLC-Systems see our General Catalog

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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