产品说明
应用
5-(N-Methyl-N-isobutyl)amiloride is a potent blocker of the Na2/H+ antiport. 5-(N-Methyl-N-isobutyl)amiloride has been used to study early cellular response to acidosis.
包装
25 mg in poly bottle
生化/生理作用
Potent blocker of the Na+/H+ antiport. Possible antitumor agent.
基本信息
| 经验(实验)分子式 | C11H18ClN7O |
| 分子量 | 299.76 |
| MDL编号 | MFCD00078567 |
| PubChem化学物质编号 | 24278228 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| mp | 200-201 ℃ |
| 溶解性 | methanol: 9.80-10.20 mg/mL, clear, pale yellow to yellow |
| 储存温度 | 2-8℃ |
| SMILES string | CC(C)CN(C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N |
| InChI | 1S/C11H18ClN7O/c1-5(2)4-19(3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20) |
| InChI key | RVIUMPLAOXSSGN-UHFFFAOYSA-N |
| Gene Information | human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340) mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278) rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
