产品说明
一般描述
Apolipoprotein J is a ubiquitously expressed glycoprotein that is involved in the differentiation and proliferation of cells. Apolipoprotein J in conjunction with apolipoprotein E may affect the onset of amyloid-beta deposition, and also may be involved in the local toxicity associated with these deposits. Hence, apolipoprotein J may function as a cerebrospinal fluid marker for Alzheimer′s disease.
Goat anti-apolipoprotein J antibody recognizes human apolipoprotein J and has negligible cross-reactivity with Type A-I, A-II, B, C-I, C-II, C-III and E apolipoproteins.
免疫原
Apolipoprotein Type J isolated from human plasma by density gradient centrifugation followed by HPLC purification.
应用
HEK293 cells were transfected with either an expression vector to over expression Clusterin or siRNA to knock down expression of Clusterin. Clusterin levels were monitored by western blot using goat anti-Clusterin antibody at 1:1000.
Goat anti-apolipoprotein J antibody can be used for immunohistochemistry applications using formalin-fixed, paraffin-embedded sections at a concentration ranging from 1:50-1:200. The antibody is also suitable for use in ELISA.
外形
Solution in 0.1 M sodium borate, 0.075 M sodium chloride, 0.005 M EDTA, pH 8.0, and 0.01% sodium azide as preservative.
基本信息
| MDL编号 | MFCD01092275 |
产品性质
| 质量水平 | 200 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | ELISA: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 western blot: 1:5,000-1:10,000 |
| UniProt登记号 | P10909 |
| 运输 | dry ice |
| 储存温度 | 2-8℃ |
| Gene Information | human ... CLU(1191) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H361d |
| 预防措施声明 | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| 危险分类 | Repr. 2 |
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
Sigma-Aldrich
m.cnreagent.com
