产品说明
一般描述
ACTR associates with estrogen receptors in breast and ovarian cancers and stimulates transcription. Hence, ACTR has been implicated in the carcinogenesis of breast and ovarian tumors. Mouse monoclonal Anti-ACTR/AIB1 antibody recognizes human ACTR (150kD) and another doublet (110kD) by immunoblotting.
ACTR, a nuclear receptor coactivator, is also referred to as amplified in breast cancer 1 (AIB1), thyroid hormone receptor activator molecule-1 (TRAM-1), receptor-associated coactivator 3 (RAC3 and SRC3).
免疫原
GST fusion protein containing amino acids 605-1294 of human ACTR.
应用
Mouse monoclonal can be used for immunoprecipitation (15μL using 500μg of a BG-1 ovarian cell RIPA lysate) and western blot (1:500, using RIPA lysates of BG-1 ovarian cancer cells) assays.
外形
The product is supplied as mouse ascites fluid, containing 30% glycerol and 0.035% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD02095791 |
NACRES | NA.41 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | ascites fluid |
antibody product type | primary antibodies |
克隆 | AX 15, monoclonal |
分子量 | antigen 150 kDa |
包含 | 0.035% sodium azide 30% glycerol |
species reactivity | human |
technique(s) | immunoprecipitation (IP): 15 μL using 500 μg of a BG-1 ovarian cell RIPA lysate. western blot (chemiluminescent): 1:500 using RIPA lysates of BG-1 ovarian cancer cells |
同位素/亚型 | IgG |
UniProt登记号 | Q9Y6Q9 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... NCOA3(8202) |
Sigma-Aldrich