产品说明
一般描述
Acinus is a ubiquitous protein that induces apoptotic chromatin condensation in cells. This protein is cleaved by caspase-3 and an additional unknown protease that subsequently generates a small active peptide p17. This small peptide causes in vitro condensation of chromatin when it is added to purified nuclei. In humans and mice, there are three distinct splice variants, namely, AcinusL, AcinusS, and AcinusS′. Rabbit anti-acinus, C-terminal antibody binds to human acinus (approx. 220 kDa) by immunoblotting.
免疫原
synthetic peptide corresponding to amino acids 1329-1341 of human AcinusL, 602-614 of human AcinusS′ and 571-583 of human AcinusS.
应用
Rabbit anti-acinus, C-terminal antibody can be used for western blot assays at a concentration of 0.25-0.5 μg/mL.
包装
100 μg in glass bottle
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
基本信息
MDL编号 | MFCD03096576 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | PBS solution |
分子量 | antigen ~220 kDa |
species reactivity | human |
浓度 | ~0.5 mg/mL |
technique(s) | western blot: 0.25-0.5 μg/mL |
UniProt登记号 | Q9UKV3 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... ACIN1(22985) |
Sigma-Aldrich