产品说明
一般描述
Recognizes the furin cleavage site (58-60 kDa) of ADAM-10. Detects the latent form of the enzyme.
ADAM is a member of the disintegrin and metalloproteinase family of proteins which possess both adhesion and zinc protease functions. ADAM-10 is a sheddase with both a secreted and membrane-bound form. ADAM-10 null mice are embryonically lethal with neural and cardiac defects. Rabbit anti-ADAM-10 antibody can localize human ADAM 10 and does not detect other ADAMs.
免疫原
synthetic peptide corresponding to the prohormone convertase (PC) cleavage site of human ADAM-10.
应用
Rabbit anti-ADAM-10 antibody has been used for western blot assays.
包装
100 μg in glass bottle
外形
Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD04040147 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous glycerol solution |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | western blot: 1:1,000 |
| UniProt登记号 | O14672 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ADAM10(102) |
Sigma-Aldrich
m.cnreagent.com
