产品说明
免疫原
Recombinant low density lipoprotein receptor
Immunogen Sequence: GI # 4504975, sequence 29-205
应用
Anti-LDLR antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein encoded by the LDLR gene in humans and belongs to the low density lipoprotein receptor gene family. It is located on chromosome number 19. LDL receptor is a mosaic protein constituiting of exons shared with different proteins. It is crucial for maintenance of cholesterol homeostasis. A deficiency in LDLR leads to hypercholesterolemia. LDLR is a type I transmembrane protein that needs O-glycosylation for stable expression at the cell surface. Mutation in this gene may cause familial hypercholesterolemia (FH), an autosomal dominant disease.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00282350 |
NACRES | NA.41 |
产品性质
生物来源 | chicken |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | human, rat, mouse |
manufacturer/tradename | Genway 15-288-22458A |
technique(s) | western blot: suitable |
NCBI登记号 | NP_000518.1 |
UniProt登记号 | P01130 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... LDLR(3949) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich