Rufinamide

产品名称：

106308-44-5
Rufinamide
1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-Triazole-4-carboxamide

产品介绍：

产品说明

应用

Rufinamide has been used to test its analgesic effect on neuropathic pain in spared nerve injury (SNI) model.

包装

10, 50 mg in glass bottle

生化/生理作用

Rufinamide may elicit inhibition of the sodium channels and block action potential generation. This property makes it an antiepileptic drug for treating epilepsy disorders like Lennox-Gastaut syndrome.
Broad-spectrum anticonvulsant.

特点和优势

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

诊断含义

Effective therapy for partial seizures in adults and childhood seizures in Lennox-Gastaut syndrome.

基本信息

经验(实验)分子式	C₁₀H₈F₂N₄O
分子量	238.19
MDL编号	MFCD00865314
PubChem化学物质编号	24724595
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white
溶解性	DMSO: 9 mg/mL
创始人	Novartis
储存温度	−20℃
SMILES string	NC(=O)c1cn(Cc2c(F)cccc2F)nn1
InChI	1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3,5H,4H2,(H2,13,17)
InChI key	POGQSBRIGCQNEG-UHFFFAOYSA-N
Gene Information	human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

安全信息

象形图
警示用语：	Warning
危险声明	H336 - H351 - H361fd
预防措施声明	P201 - P202 - P261 - P271 - P280 - P308 + P313
危险分类	Carc. 2 - Repr. 2 - STOT SE 3
靶器官	Central nervous system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable