产品说明
一般描述
Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist.
应用
Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats.
生化/生理作用
Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery.
基本信息
| 经验(实验)分子式 | C21H27ClN2O2 · 2HCl |
| 分子量 | 447.83 |
| EC 号 | 218-586-3 |
| MDL编号 | MFCD00058200 |
| PubChem化学物质编号 | 24895830 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% |
| 形式 | powder |
| 溶解性 | H2O: soluble alcohol: soluble chloroform: soluble |
| SMILES string | Cl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 |
| InChI | 1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H |
| InChI key | ANOMHKZSQFYSBR-UHFFFAOYSA-N |
| Gene Information | human ... HRH1(3269) |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 - H336 - H361d |
| 预防措施声明 | P201 - P301 + P312 + P330 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Repr. 2 - STOT SE 3 |
| 靶器官 | Central nervous system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
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