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BAFF active human

活性BAFF 人

品牌
Sigma-Aldrich
货号
B0939
规格纯度
Animal-component free, recombinant, expressed in Nicotiana, >97% (SDS-PAGE)
参考价格
7152.8 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
BAFF active human
TALL-1
Dendritic cell-derived TNF-like molecule
TNF- and APOL-related leukocyte expressed ligand 1
B lymphocyte stimulator
B-cell-activating factor BAFF
BLyS
活性BAFF 人
产品介绍:

产品说明

一般描述

BAFF (B lymphocyte activating factor) is a member of the tumor necrosis factor (TNF) ligand family which is expressed in T Cells, macrophages, monocytes and dendritic cells. It is also known as BLyS, THANK, TALL, zTNF4 and TNFS20. BAFF enhances B cell survival in vitro and has emerged as a key regulator of peripheric B cell and it is vital homeostatic cytokine for B cells that helps regulate both innate and adaptive immune responses. BAFF binds to three TNF receptors: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium modulator and cyclophilin ligand interactor(TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF 13C).The human BAFF gene code for a 285 amino acids type II transmembrane protein. Recombinant human soluble BAFF is a 151 amino acids containing the TNF-like portion of the extracellular domain of BAFF.

外形

Lyophilized from a 20 mM PBS buffer at pH 7 and 0.2 M NaCl.

重悬

Lyophilized protein should be reconstituted in water to a concentration of 25 - 50 ng /μl. Due to the protein nature, dimmers and multimers may be observed.

分析说明

The activity is determined by dose-dependeant stimulation of proliferation B cell from Human PBMC. Cell proliferation was measured by MTT method.
*activity results may vary with PBMC donors.
ED50 ≤ 50 ng/mL

其他说明

Extinction Coefficient: E0.1% = 0.791 (A280 nm)
p.I: 6.03

基本信息

NACRESNA.32

产品性质

质量水平200
生物来源human
重组expressed in Nicotiana
测定>97% (SDS-PAGE)
形式lyophilized
效能≤50 ng/mL ED50
分子量 18-20 kDa (a glycosilated polypeptide chain containing 151 amino acids)
包装pkg of 10 μg
储存条件avoid repeated freeze/thaw cycles
杂质 Endotoxin, tested (LAL test, < 0.04 EU/ ug protein)
UniProt登记号Q9Y275
储存温度−20℃
Gene Informationhuman ... TNFSF13B(10673)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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