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Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse

品牌
Sigma-Aldrich
货号
B9561
规格纯度
clone 35909, purified immunoglobulin, lyophilized powder
参考价格
5600.91 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse
Anti-BDNF
产品介绍:

产品说明

一般描述

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The influence of BDNF is mediated by its binding to TrkB receptor and sometimes the receptor p75NTR. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins. The secretion of BDNF is highly regulated at both transcriptional and translational levels since it is involved in the proper function of neuronal circuit and development of cognitive functions. The deficits in BDNF functions are implicated in a number of neurodegenerative disorders such as Huntington′s disease, schizophrenia and dementia
Monoclonal Anti-Brain-derived Neurotrophic Factor detects human BDNF.

免疫原

purified, Sf21-derived recombinant human brain-derived neurotrophic factor.

应用

Monoclonal Anti-Brain-derived Neurotrophic Factor may be used to detect human BDNF by flow cytometry using a working antibody concentration of 25 μg/ml.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01633045

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆35909, monoclonal
形式lyophilized powder
species reactivityhuman
technique(s)flow cytometry: 25 μg/mL
同位素/亚型IgG1
UniProt登记号P23560
储存温度−20℃
Gene Informationhuman ... BDNF(627)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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