产品说明
生化/生理作用
BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.
BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils. Its specific receptor BLR1 is a G protein-coupled receptor originally isolated from Burkitt′s lymphoma cells. Among cells of the hematopoietic lineages, the expression of BRL1, now designated CXCR5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.
The biological activity of human BLC/BCA-1 is measured by its ability to chemoattract mouse BaF/3 cells transfected with human CXCR5.
外形
Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 50 μg bovine serum albumin per 1 μg of cytokine.
基本信息
MDL编号 | MFCD01867020 |
NACRES | NA.32 |
产品性质
质量水平 | 200 |
生物来源 | human |
重组 | expressed in E. coli |
测定 | ≥95% (SDS-PAGE) |
形式 | lyophilized powder |
效能 | 0.1000 μg/mL |
分子量 | apparent mol wt 8.7 kDa by SDS-PAGE (reducing) |
包装 | pkg of 25 μg |
储存条件 | avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.) |
technique(s) | cell culture | mammalian: suitable |
杂质 | endotoxin, tested |
UniProt登记号 | O43927 |
储存温度 | −20℃ |
Gene Information | human ... CXCL13(10563) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 + H332 - H319 |
预防措施声明 | P261 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich