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Ibandronate sodium salt

Ibandronate 钠盐 一水合物

品牌
Sigma-Aldrich
CAS
138844-81-2
货号
I5784
规格纯度
≥97% (NMR), solid
参考价格
1127.64 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
138844-81-2
Ibandronate sodium salt
Bondronat
(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium
Ibandronate 钠盐 一水合物
(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid 钠 一水合物
Boniva
产品介绍:

产品说明

应用

Ibandronate sodium salt has been used to study its effect on the proliferation and ultrastructure of Leishmania and Giardia by the generation of concentration curves. It has also been used to elucidate the route by which nitrogen-containing bisphosphonates (N-BPs) enter the cytosol and inhibit their molecular target.

包装

10, 50 mg in glass bottle

生化/生理作用

Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium is also a bone resorption inhibitor. It has been investigated for in vitro anti-tumor effects, such as apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, and inhibition of angiogenesis and for its in vivo role in various cancers including breast and prostate cancers.
Ibandronate is a nitrogen-containing bisphosphonate (N-BP). It potentially inhibits mevalonate pathway in osteoclasts. Thus, ibandronate is effectively used to treat osteoporosis and other bone-related diseases.

特点和优势

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C9H22NNaO7P2
分子量341.21
MDL编号MFCD07197214
PubChem化学物质编号329815388
NACRESNA.77

产品性质

质量水平100
测定≥97% (NMR)
形式solid
储存条件protect from light
颜色 white
溶解性H2O: >10 mg/mL
创始人Roche
储存温度2-8℃
SMILES string[Na+].CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)([O-])=O
InChI1S/C9H23NO7P2.Na/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);/q;+1/p-1
InChI keyLXLBEOAZMZAZND-UHFFFAOYSA-M
Gene Informationhuman ... FDPS(2224)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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