6-氯-9-(4-二乙氨基-1-甲基丁氨基)-2-甲氧基吖啶二盐酸盐

产品名称：

69-05-6
Quinacrine dihydrochloride
6-Chloro-9-(4-diethylamino-1-methylbutylamino)-2-methoxyacridine dihydrochloride
Atebrin dihydrochloride
Mepacrine dihydrochloride
Mepacrine
喹吖因二盐酸盐
6-氯-9-(4-二乙氨基-1-甲基丁氨基)-2-甲氧基吖啶二盐酸盐
米帕林二盐酸盐
阿的平二盐酸盐

产品介绍：

产品说明

一般描述

A non-specific phospholipase A₂ (PLA₂) inhibitor. Acts as an acetylcholine receptor antagonist. Suppresses glibenclamide-sensitive K⁺-currents (IC₅₀ = 4.4 µM). Also inhibits monoamine oxidase (MAO).

包装

100 mg in Plastic ampoule

生化/生理作用

Target IC₅₀: 4.4 µM in suppressing glibenclamide-sensitive K+-currents
Product does not compete with ATP.
Reversible: no
非选择性 MAO-A/B 抑制剂。
Cell permeable: no

警告

Toxicity: Harmful (C)

重悬

Stock solutions are stable for up to 60 h at 20°C.

其他说明

Holscher, C. 1995. Neurobiol. Learn. Mem. 63, 206.
Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117.
Sargent, C.A., et al 1992. J. Pharmacol. Exp. Ther.262, 1161.
Voorhis, B.J., et al. 1992. Invertebr. Reprod. Dev.21, 33.
Murakami, M., et al. 1991. Biochem. Biophys. Res. Commun.181, 714.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₃H₃₀ClN₃O · 2HCl
分子量	472.88
Beilstein	4834013
MDL编号	MFCD00012659

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated (hygroscopic) protect from light
颜色	yellow
溶解性	water: soluble
运输	ambient
储存温度	10-30℃
SMILES string	Cl[H].Cl[H].CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13
InChI	1S/C23H30ClN3O.2ClH/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23;;/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26);2*1H
InChI key	UDKVBVICMUEIKS-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3

Quinacrine dihydrochloride

喹吖因 二盐酸盐

喹吖因二盐酸盐