Tetrabenazine

产品名称：

58-46-8
Tetrabenazine
9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2H-benzo[a]quinolizin-2-one

产品介绍：

产品说明

应用

Tetrabenazine has been used for dopamine uptake assays in mouse brain cells¹. Tetrabenazine has also been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells².

包装

10, 50 mg in glass bottle

生化/生理作用

Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.

特点和优势

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

制备说明

Tetrabenazine is soluble in DMSO at a concentration that is greater than 10 mg/ml and is insoluble in water.

基本信息

经验(实验)分子式	C₁₉H₂₇NO₃
分子量	317.42
Beilstein	40090
EC 号	200-383-6
MDL编号	MFCD08461052
PubChem化学物质编号	329826731
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
溶解性	DMSO: >10 mg/mL H₂O: insoluble
创始人	Roche
储存温度	2-8℃
SMILES string	COc1cc2CCN3C[C@@H](CC(C)C)C(=O)CC3c2cc1OC
InChI	1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1
InChI key	MKJIEFSOBYUXJB-GDBMZVCRSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves