CGS-15943

产品名称：

104615-18-1
CGS-15943
9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine

产品介绍：

产品说明

应用

CGS-15943 has been used as a non-selective adenosine receptor antagonist to study its effects on the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and hepatocellular carcinoma (HCC). It has also been used as a non-selective adenosine receptor antagonist to investigate the mechanism underlying adenosine inhibition on cholangiocarcinoma (CCA) cells.

包装

25 mg in poly bottle

生化/生理作用

CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity.

基本信息

经验(实验)分子式	C₁₃H₈ClN₅O
分子量	285.69
MDL编号	MFCD01529897
PubChem化学物质编号	24277704
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white
溶解性	DMSO: >10 mg/mL H₂O: insoluble
储存温度	room temp
SMILES string	Nc1nc2ccc(Cl)cc2c3nc(nn13)-c4ccco4
InChI	1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16)
InChI key	MSJODEOZODDVGW-UHFFFAOYSA-N
Gene Information	human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140) rat ... Adora1(29290), Adora2a(25369), Adora2b(29316)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)