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位置:首页 > 品牌 > Sigma-Aldrich > Chondroitinase B from Flavobacterium heparinum

Chondroitinase B from Flavobacterium heparinum

品牌
Sigma-Aldrich
CAS
52227-83-5
货号
C8058
规格纯度
lyophilized powder (with BSA as stabilizer)
参考价格
8211.34 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
52227-83-5
Chondroitinase B from Flavobacterium heparinum
Chondroitin sulfate B lyase
产品介绍:

产品说明

应用

Chondroitinase B from Flavobacterium heparinum has been used in a study to assess the structural characterization and antithrombin activity of dermatan sulfate. Chondroitinase B from Flavobacterium heparinum has also been used in a study to investigate the chondroitin lyase action pattern via liquid chromatography–mass spectrometry.
The enzyme from Sigma has been used for the analysis of the frequency of iduronic acid in dermatan sulfate dodecasaccharide. It has also been used to digest dermatan sufate (DS) in melanoma cells. This digestion resulted in decreased proliferation and invasiveness of tumor cells, thereby suggesting a role for DS in metastasis.

生化/生理作用

Chondroitinase B degrades only chondroitin sulphate B producing oligo- and tetra-saccharides, and an unsaturated 4-sulphated disaccharide. It has an optimum temperature of 20 ℃ and an optimum pH of 8.0. The enzyme activity is inhibited by 50% using 0.1 M NaCI. Co2+, Fe3+ and Ba2+ also inhibit its activity.

单位定义

One unit will form 0.1 μmole of unsaturated uronic acid per hr at pH 7.5 at 25℃ using chondroitin sulfate B as substrate.

基本信息

MDL编号MFCD00166444
NACRESNA.54

产品性质

质量水平200
形式lyophilized powder (with BSA as stabilizer)
运输dry ice
储存温度−20℃

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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